Chromosome Evil 2 similar games & best alternatives

Chromosome Evil 2

PC (Microsoft Windows) • 2024

Should you play it?

Dive deep into this Lovecraft-inspired RTS survival for a second time. Assemble your strike team and manage your convoy. It's up to you to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?

What works
  • Deep tactical and strategic gameplay
  • Meaningful resource and squad management
  • Multiple endings and replayability
  • Active developer support and frequent updates
  • Accessible on low-end pcs
Things to keep in mind
  • Numerous bugs and crashes reported
  • Clunky ui and inventory management
  • Pathfinding and unit movement issues
  • Steep learning curve and grind
  • Some balance issues with ammo scarcity and enemy difficulty spikes

What to play next

Top picks

Games that feel the closest overall

  • Chromosome Evil

  • Space Hulk: Ascension (Classic)

  • Lords of Magic: Special Edition

  • Darkest Dungeon®

  • Rencounter

  • Sandwalkers

  • The Bard's Tale Trilogy

  • Star Wolves

  • Freedom Force vs. the Third Reich

Search more ->

Hidden Gems

Less popular games with surprisingly high similarity

  • Star Wolves 3: Civil War

  • Heroes of Steel RPG

  • Siege of Dungeon

If you liked…

Recommendations by what you enjoyed most

  • Strategy

    Don't Starve Together

  • Survival

    Heads Will Roll: Reforged

  • Autonomy

    Phoenix Point

Similarity map

Explore nearby similar games and see why they’re close.

How to use the graph
Similarity map

Each dot is a game. They are arranged from the same motivation profile as in the “Why this game works” section below. Closer dots usually mean more similar reasons to play (exploration, competition, relaxation, etc.)—not that one game is “better” than another.

  • Purple star: this page’s game — everything on the map is relative to it.
  • Coloured chips: click to highlight games that mainly differ on that motivation; click again to reset.
  • Dotted line: link between this page’s game and the one selected for comparison.
  • Hover a dot to preview that game in the panel on the right; click to keep that comparison.
  • Scroll or double-click the chart to zoom out and see more games.

Why don’t the axes read like a score? This view uses t-SNE: it only keeps who is close to whom. The scales are not “good to bad” or hours played—they separate groups on the map. Read distance between dots, not the axis numbers (hidden on purpose).

Chromosome Evil 2: Broadly representative of its motivational profile, with a few distinct shifts. Motivations that often define this kind of title include Survival, Violence, Fellowship, Intimacy. Here, the score leans higher than usual among comparable games on Cooperation, Leadership. It leans lower than usual among comparable games on Relaxation.

Why this game works

A motivational profile of the game, with the closest similar game for each player motivation.

  • Autonomy

    Game with the same Autonomy vibe

    4

    "Players have significant control over squad composition, multi-classing, tactical aiming, and strategic decisions on base management and diplomacy."

    Capsule for Phoenix Point Phoenix Point

    "Players have significant control over squad composition, equipment, base management, and strategic decisions on the world map."

  • Competence

    Game with the same Competence vibe

    4

    "Game requires tactical thinking, skillful combat, and strategic resource management with meaningful feedback."

    Capsule for Dungeonmans Dungeonmans

    "The game requires skillful resource management, tactical combat, and strategic planning with meaningful feedback and progression."

  • Competition

    Game with the same Competition vibe

    -3

    "Focus is on personal survival and progression rather than competing against other players; no mention of PvP or leaderboards."

    Capsule for FatalZone: Outbreak FatalZone: Outbreak

    "Focus is on personal survival and progression rather than competing against other players; no PvP or leaderboards mentioned."

  • Continuation

    Game with the same Continuation vibe

    4

    "Players report long play sessions, replayability with multiple endings, and habitual engagement with the game."

    Capsule for Beyond Shadowgate Beyond Shadowgate

    "Players report long play sessions, replayability with multiple endings, and habitual engagement despite some grind and bugs."

  • Cooperation

    Game with the same Cooperation vibe

    2

    "Teamwork within player’s squad is important, but multiplayer cooperation is not present."

    Capsule for Dead Grid Dead Grid

    "Teamwork within the squad and convoy management is important, but multiplayer cooperation is not present."

  • Creativity

    Game with the same Creativity vibe

    3

    "Players customize their base layouts, equipment, and upgrade paths, allowing creative strategic choices."

    Capsule for Outpost Outpost

    "Customization of characters, equipment, and base upgrades allows creative approaches to strategy and loadouts."

  • Domination

    Game with the same Domination vibe

    -4

    "Interactions are balanced and cooperative within the squad; no evidence of dominance or power assertion over others."

    Capsule for StrikeForce Kitty StrikeForce Kitty

    "Interactions are balanced and cooperative within the squad; no evidence of dominance or power over others."

  • Escapism

    Game with the same Escapism vibe

    4

    "Immersive post-apocalyptic setting and tactical gameplay provide a strong escape from real life."

    Capsule for Chains of Freedom Chains of Freedom

    "The post-apocalyptic, horror-themed setting and tactical gameplay provide immersive escape from real life."

  • Expectation

    Game with the same Expectation vibe

    -4

    "Players engage voluntarily out of interest and enjoyment; no indication of obligation or external pressure."

    Capsule for Black Myth: Wukong Black Myth: Wukong

    "Players engage voluntarily out of interest and enjoyment; no indication of obligation or external pressure."

  • Experimenting

    Game with the same Experimenting vibe

    4

    "Players experiment with different squad leaders, equipment, and tactics to overcome varied challenges."

    Capsule for MENACE MENACE

    "Players experiment with different squad builds, equipment, strategies, and resource management approaches."

  • Exploration

    Game with the same Exploration vibe

    3

    "Exploration of maps and discovery of resources and secrets is a core gameplay element."

    Capsule for Heroes of Might & Magic V: Tribes of the East Heroes of Might & Magic V: Tribes of the East

    "Exploration of varied maps and discovery of secrets and loot is a core gameplay element."

  • Expression

    Game with the same Expression vibe

    2

    "Character selection and build customization allow some self-expression; no deep avatar personalization."

    Capsule for Black Future '88 Black Future '88

    "Some character naming and equipment customization allow limited self-expression, though no deep avatar personalization."

  • Fantasy

    Game with the same Fantasy vibe

    4

    "The game features a fictional zombie apocalypse setting with horror and supernatural elements."

    Capsule for Propagation: Paradise Hotel Propagation: Paradise Hotel

    "The game features a fictional post-apocalyptic world with mutated zombies and Lovecraftian horror elements."

  • Fellowship

    Game with the same Fellowship vibe

    -3

    "Minimal social or community interaction within gameplay; focus is on solo team management experience."

    Capsule for F1® Manager 2024 F1® Manager 2024

    "Gameplay is focused on individual player experience managing their own squad; minimal social interaction."

  • Growth

    Game with the same Growth vibe

    4

    "Players develop characters through leveling jobs, learning skills, and improving equipment, showing clear progression and learning."

    Capsule for Dungeon Antiqua 2 Dungeon Antiqua 2

    "Players develop characters through skills, training, and research, showing clear learning and progression."

  • Health

    Game with the same Health vibe

    -4

    "Sedentary gameplay with no physical activity; some players report fatigue from micromanagement."

    Capsule for Ways of Alchemy Ways of Alchemy

    "Gameplay is sedentary with no physical activity; some reports of frustration and fatigue from micromanagement."

  • Idle

    Game with the same Idle vibe

    -3

    "Requires active attention and management; not a casual or background game."

    Capsule for Cities in Motion Cities in Motion

    "Game requires active attention and micromanagement; no indication of casual or background play."

  • Intimacy

    Game with the same Intimacy vibe

    -4

    "No evidence of close social relationships or emotional sharing; interactions are minimal and task-focused."

    Capsule for Sudden Strike 5 Sudden Strike 5

    "No evidence of close social relationships or emotional sharing; interactions are task-focused and tactical."

  • Leadership

    Game with the same Leadership vibe

    3

    "Players lead and manage squads and base operations, making strategic and tactical decisions."

    Capsule for SPARTA 2035 SPARTA 2035

    "Players lead and manage squads and convoy personnel, making strategic and tactical decisions."

  • Progression

    Game with the same Progression vibe

    4

    "Strong emphasis on accumulating items, upgrading base and vehicles, and character leveling."

    Capsule for Taora : Beginning Taora : Beginning

    "Strong emphasis on accumulating resources, upgrading vehicles, researching tech, and leveling characters."

  • Relaxation

    Game with the same Relaxation vibe

    -2

    "Game is tense and challenging with frequent threats and resource pressure, limiting relaxation."

    Capsule for LIFE EFFECT Survival LIFE EFFECT Survival

    "The game is tense and challenging with time pressure and evolving threats, limiting relaxation."

  • Sensation

    Game with the same Sensation vibe

    2

    "Visual pixel art and atmospheric soundtrack provide sensory stimulation, though not intense or overwhelming."

    Capsule for Technobabylon Technobabylon

    "The pixel art and soundtrack provide atmospheric sensory stimulation, though some find it repetitive."

  • Status

    Game with the same Status vibe

    -4

    "No social recognition or popularity mechanics; focus is on individual achievement."

    Capsule for Deepest Chamber: Resurrection Deepest Chamber: Resurrection

    "No social recognition or popularity elements; focus is on individual achievement and survival."

  • Story

    Game with the same Story vibe

    3

    "Game has a developing narrative with multiple missions and endings, though incomplete and sometimes buggy."

    Capsule for Bitardia Bitardia

    "The game features a narrative campaign with multiple endings and story missions integrated with gameplay."

  • Strategy

    Game with the same Strategy vibe

    5

    "High mental challenge requiring planning, resource management, and tactical combat."

    Capsule for Don't Starve Together Don't Starve Together

    "High mental challenge requiring planning, resource allocation, tactical combat, and problem solving."

  • Thrill

    Game with the same Thrill vibe

    4

    "High suspense and tension from difficult missions and unpredictable enemy behavior."

    Capsule for X-COM: Terror From the Deep X-COM: Terror From the Deep

    "The evolving enemy threat and permadeath create suspense and tension during missions."

  • Value

    Game with the same Value vibe

    3

    "Players report good value for money with many hours of gameplay and active developer support."

    Capsule for Winnie's Hole Winnie's Hole

    "Players report good value for money with many hours of gameplay and active developer support."

  • Violence

    Game with the same Violence vibe

    4

    "Combat against zombies with melee and ranged attacks is central, involving destruction and killing."

    Capsule for Wanna Survive Wanna Survive

    "Combat against zombies and mutants is central, involving melee and ranged weapons with destruction."

  • Survival

    Game with the same Survival vibe

    5

    "Core gameplay revolves around managing resources, avoiding death, and overcoming threats."

    Capsule for Heads Will Roll: Reforged Heads Will Roll: Reforged

    "Core gameplay revolves around managing resources, avoiding death, and overcoming escalating threats."

Last update: 19/07/2026