Chromosome Evil similar games & best alternatives

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Chromosome Evil

PC (Microsoft Windows) • 2022

Should you play it?

Dive deep into this Lovecraft-inspired RTS survival. Assemble your team using different classes, skills, and weaponry. It's up to your squad to survive the onslaught of nightmares that are surely coming your way. Will you find the source of the darkness?

What works
  • Challenging tactical gameplay
  • Strong atmosphere and story
  • Meaningful resource management
  • Multiple endings and replayability
  • Active developer support
Things to keep in mind
  • Clunky controls and pathfinding
  • Some bugs and crashes
  • Steep difficulty curve
  • Limited ui and tutorial clarity
  • Lack of multiplayer or social features

What to play next

Top picks

Games that feel the closest overall

  • Space Hulk: Ascension (Classic)

  • Lords of Magic: Special Edition

  • Darkest Dungeon®

  • Rencounter

  • Star Wolves

  • Judgment: Apocalypse Survival Simulation

  • Sandwalkers

  • Freedom Force vs. the Third Reich

  • The Bard's Tale Trilogy
Hidden Gems

Less popular games with surprisingly high similarity

  • Rencounter

  • Star Wolves

  • Sandwalkers
If you liked…

Recommendations by what you enjoyed most

  • Strategy

    Master of Command
  • Survival

    Human Host
  • Competence

    Dungeonmans

Similarity map

Explore nearby similar games and see why they’re close.

How to use the graph
Similarity map

Each dot is a game. They are arranged from the same motivation profile as in the “Why this game works” section below. Closer dots usually mean more similar reasons to play (exploration, competition, relaxation, etc.)—not that one game is “better” than another.

  • Purple star: this page’s game — everything on the map is relative to it.
  • Coloured chips: click to highlight games that mainly differ on that motivation; click again to reset.
  • Dotted line: link between this page’s game and the one selected for comparison.
  • Hover a dot for a screenshot preview, score, and top score gaps; click to compare in the panel on the right.
  • Scroll or double-click the chart to zoom out and see more games.

Why don’t the axes read like a score? This view uses t-SNE: it only keeps who is close to whom. The scales are not “good to bad” or hours played—they separate groups on the map. Read distance between dots, not the axis numbers (hidden on purpose).

Chromosome Evil: Broadly representative of its motivational profile, with a few distinct shifts. Motivations that often define this kind of title include Violence, Survival, Fellowship, Intimacy. Here, the score leans higher than usual among comparable games on Cooperation, Leadership. It leans lower than usual among comparable games on Relaxation.

Why this game works

A motivational profile of the game, with the closest similar game for each player motivation.

  • Autonomy

    Game with the same Autonomy vibe

    3

    "Players can choose squad members, customize builds, and make tactical decisions in combat and base management, though some mission structures are fixed."

    Capsule for Vigilantes Vigilantes

    "Players can choose squad composition, upgrade paths, and strategic decisions, though some mission structure is linear."

  • Competence

    Game with the same Competence vibe

    4

    "Game requires tactical thinking, skillful combat, and strategic resource management with meaningful feedback."

    Capsule for Dungeonmans Dungeonmans

    "Game requires skillful resource management, tactical control, and decision-making with meaningful feedback and challenge."

  • Competition

    Game with the same Competition vibe

    -3

    "Focus is on personal survival and progression rather than direct competition with other players."

    Capsule for Gothic 1 Gothic 1

    "Focus is on personal survival and progression rather than competing against other players."

  • Continuation

    Game with the same Continuation vibe

    4

    "Players report long play sessions, replayability with multiple builds and endings, and habitual engagement."

    Capsule for Verho - Curse of Faces Verho - Curse of Faces

    "Players report long sessions, repeated playthroughs, and engagement with multiple endings and upgrades."

  • Cooperation

    Game with the same Cooperation vibe

    2

    "Squad-based gameplay involves working with AI teammates, but no multiplayer or player-to-player cooperation."

    Capsule for Mass Effect™ Legendary Edition Mass Effect™ Legendary Edition

    "Squad-based gameplay involves managing multiple characters with complementary roles, though multiplayer is absent."

  • Creativity

    Game with the same Creativity vibe

    2

    "Players customize squad loadouts, assign traits, and choose mission paths, offering some creative expression within structured gameplay."

    Capsule for Broken Lines Broken Lines

    "Players customize squad loadouts and upgrades; some procedural map variation adds novelty."

  • Domination

    Game with the same Domination vibe

    -4

    "Interactions are balanced and cooperative within the squad; no evidence of dominance or power assertion over others."

    Capsule for StrikeForce Kitty StrikeForce Kitty

    "Interactions emphasize survival and teamwork within squad; no evidence of dominance or power over others."

  • Escapism

    Game with the same Escapism vibe

    4

    "Players use the game as a thrilling distraction with immersive atmosphere and horror elements."

    Capsule for Five Nights at Freddy's: Security Breach Five Nights at Freddy's: Security Breach

    "Players use the game as immersive distraction with atmospheric horror and tension."

  • Expectation

    Game with the same Expectation vibe

    -4

    "Players engage voluntarily out of interest and enjoyment, despite difficulty and frustration."

    Capsule for GTFO GTFO

    "Players engage voluntarily out of interest and enjoyment, despite difficulty and challenge."

  • Experimenting

    Game with the same Experimenting vibe

    3

    "Players explore different levels, mechanics, and strategies to overcome challenges."

    Capsule for PUSS! PUSS!

    "Players explore different strategies, squad builds, and mission approaches to overcome challenges."

  • Exploration

    Game with the same Exploration vibe

    2

    "Randomized missions and map elements encourage some discovery, though maps are limited and familiar over time."

    Capsule for The Red Solstice The Red Solstice

    "Some procedural map elements and mission choices encourage discovery, though many maps are reused."

  • Expression

    Game with the same Expression vibe

    2

    "Some character and equipment customization allows personal expression within constraints."

    Capsule for Pixel Heroes: Byte & Magic Pixel Heroes: Byte & Magic

    "Character customization and equipment upgrades allow some personal expression within constraints."

  • Fantasy

    Game with the same Fantasy vibe

    4

    "Game features folk horror, supernatural elements, and Lovecraftian themes, providing imaginative fiction."

    Capsule for The Excavation of Hob's Barrow The Excavation of Hob's Barrow

    "Game features Lovecraftian horror, zombies, and supernatural elements in a fictional setting."

  • Fellowship

    Game with the same Fellowship vibe

    -3

    "Primarily a single-player experience with limited social interaction or community focus."

    Capsule for The Eternal Cylinder The Eternal Cylinder

    "Primarily single-player experience with limited social interaction or community focus."

  • Growth

    Game with the same Growth vibe

    4

    "Players develop squad leaders, unlock new gear, and improve strategic capabilities over time."

    Capsule for MENACE MENACE

    "Players develop skills, unlock upgrades, and improve squad capabilities over multiple playthroughs."

  • Health

    Game with the same Health vibe

    -4

    "Sedentary gameplay with no physical activity; some players note stress from difficulty."

    Capsule for Phantom Rose Phantom Rose

    "Sedentary gameplay with no physical activity; some players report stress from difficulty."

  • Idle

    Game with the same Idle vibe

    -3

    "Requires active management and attention; some downtime but generally continuous engagement."

    Capsule for Arcade Tycoon ™ : Simulation Game Arcade Tycoon ™ : Simulation Game

    "Requires focused attention and micromanagement; some downtime but generally active engagement."

  • Intimacy

    Game with the same Intimacy vibe

    -4

    "Limited social connection; interactions mostly tactical and competitive rather than emotional or close."

    Capsule for Panzer Corps Gold Panzer Corps Gold

    "Limited social connection; interactions mostly tactical and functional within squad."

  • Leadership

    Game with the same Leadership vibe

    3

    "Player leads and manages a squad, making strategic decisions and directing actions."

    Capsule for Halfway Halfway

    "Player leads and manages a squad, making strategic and tactical decisions."

  • Progression

    Game with the same Progression vibe

    4

    "Strong emphasis on accumulating upgrades, unlocking characters, and improving equipment."

    Capsule for Super Motherload Super Motherload

    "Strong emphasis on upgrading characters, equipment, and vehicle to advance through the game."

  • Relaxation

    Game with the same Relaxation vibe

    -2

    "Game is tense and challenging, often inducing stress rather than relaxation."

    Capsule for Fate of the World: Tipping Point Fate of the World: Tipping Point

    "Game is tense and challenging, inducing stress rather than relaxation."

  • Sensation

    Game with the same Sensation vibe

    3

    "Atmospheric audio and visuals provide immersive sensory experiences."

    Capsule for Barotrauma Barotrauma

    "Atmospheric audio and pixel art visuals provide immersive sensory experience."

  • Status

    Game with the same Status vibe

    -4

    "No social recognition or ranking systems; focus is on individual progress."

    Capsule for Gas Station Simulator: Prologue - Early Days Gas Station Simulator: Prologue - Early Days

    "No social recognition or ranking systems; focus is on individual progress."

  • Story

    Game with the same Story vibe

    3

    "Narrative with branching paths, character development, and multiple endings provides moderate story immersion."

    Capsule for Nightmare Knight ~Sacred Maiden & Fallen Magic~ Nightmare Knight ~Sacred Maiden & Fallen Magic~

    "Narrative with multiple endings and branching paths enriches player immersion."

  • Strategy

    Game with the same Strategy vibe

    5

    "Core gameplay revolves around tactical decision-making, resource management, and strategic planning."

    Capsule for Master of Command Master of Command

    "Core gameplay revolves around tactical decision-making, resource management, and planning."

  • Thrill

    Game with the same Thrill vibe

    4

    "High suspense and tension from permadeath, resource scarcity, and unpredictable enemy encounters."

    Capsule for Sword of the Stars: The Pit Sword of the Stars: The Pit

    "High tension and suspense from resource scarcity, enemy waves, and permadeath mechanics."

  • Value

    Game with the same Value vibe

    4

    "Players find good value in the game’s content, price, and replayability despite some bugs and performance issues."

    Capsule for Block Factory Block Factory

    "Players find good value for price with replayability and depth, despite some bugs."

  • Violence

    Game with the same Violence vibe

    3

    "Combat against zombies and enemies is central, involving shooting and destruction."

    Capsule for ISEKAI FRONTLINE ISEKAI FRONTLINE

    "Combat against zombies and monsters is central, with various weapons and melee options."

  • Survival

    Game with the same Survival vibe

    5

    "Survival mechanics, resource management, and threat avoidance are central to gameplay."

    Capsule for Human Host Human Host

    "Survival under resource constraints and escalating threats is the primary gameplay focus."

Last update: 12/07/2026